Evaluation of In-vitro antioxidant activities of Phyllanthus reticulatus extract

Abstract

Oxidative stress, caused by an imbalance between the production of reactive oxygen species (ROS) and the antioxidant defense system, plays a crucial role in the pathogenesis of various chronic diseases including cancer, cardiovascular disorders, diabetes, and neurodegenerative conditions. Medicinal plants are rich sources of natural antioxidants that can neutralize free radicals and reduce oxidative damage. Phyllanthus reticulatus, a traditionally used medicinal plant, has been reported to possess several pharmacological properties. The present study aims to evaluate the in-vitro antioxidant activity of Phyllanthus reticulatus extract using standard antioxidant assays. The plant material was extracted using suitable solvents, and the antioxidant potential was assessed through free radical scavenging methods such as DPPH and hydrogen peroxide scavenging. The results demonstrated a concentration-dependent antioxidant activity of the extract, indicating its significant free radical scavenging potential. The findings of this study support the traditional use ofPhyllanthus reticulatus and suggest that it may serve as a promising source of natural antioxidants for therapeutic applications.

Keywords: Phyllanthus reticulates, Antioxidant activity, Free radicals, In-vitro evaluation, Medicinal plants