Orodispersible Films: Innovations in Drug Delivery Systems

Abstract

Orodispersible films (ODFs) are innovative drug delivery systems designed to dissolve rapidly in the oral cavity without the need for water, offering an effective alternative for patients with swallowing difficulties, such as pediatrics and geriatrics. These films provide rapid onset of action, enhanced patient compliance, and accurate dosing. This review highlights the advantages and disadvantages of ODFs, outlines the various methods of preparation, evaluates their critical parameters, and explores their wide range of applications in the pharmaceutical field. The article concludes with an emphasis on the potential of ODFs as a versatile platform for improving drug delivery and patient outcomes.

Key words: Orodispersible films, drug delivery system, rapid disintegration, solvent casting, hot melt extrusion, bioavailability, patient compliance, taste masking, pediatric and geriatric medicine.