CNS AGENTS ON HIV/AIDS: OVERVIEW

Abstract

HIV/AIDS patients suffering from depression more often treated with various drugs like Methylphenidate, Dextroamphetamine to treat depression and also with psychoactive drugs to treat side effects like insomnia. Sometimes effects of depressant drugs like alcohol also have influence on psychological health of HIV/AIDS patients. The objective of this review article is effects of CNS agents on AIDS patient is mainly to understand the actions of the different drugs like sympathomimetics, parasympathomimetics, sympatholytics, parasympatholytics which all are drugs acting on CNS and to compile the experimental trials and the clinical trials with the various Central Nervous System(CNS) agents on patients with HIV/AIDS infection. This article reviews compilation of the experimental trials and the clinical trials on many different groups of patients with HIV/AIDS infection were selected for analysing the effects of various CNS agents like Methylphenidate, Dextroamphetamine, Psychoactive drugs and alcohol on them. HIV/AIDS patients suffering from depression were given various drugs like differences in the responses of different drugs were reviewed statistically compared and shown effects of many CNS agents in patients with HIV/AIDS infection. The aspect of review is to find out which drug is beneficial or which drug is harmful in treatment of AIDS. Further the aim to enhance the treatment with fewer side effects of CNS agents in patients with AIDS. Many drugs help in relieving depression in pateints with AIDS but may have adverse effects. Thus, the review of study has navigated effects of CNS agents on AIDS has many target oriented benefits.

KEYWORDS: HIV/AIDS, Effects of CNS Agents, Depression, Insomnia, Clinical Trials.