Formulation and Evaluation of a Poly Herbal Skin Care Lotion

Abstract

Neem and Tulsi, also known as holy trees and herbs, have been used to cure a variety of skin conditions for centuries. In this study, a poly herbal cream was made using Neem leaves (Azadirachta indica) and Tulsi leaves (Ocimum sanctum) together with other ingredients. The Tirupati Local Area was used to collect tulsi and neem leaves. Both of these plants underwent a 4-day process of shade drying before being ground into a coarse powder and sent through sieve number 22. For future research, the coarse powder was preserved. Following ethanol extraction in a soxhlet apparatus, pet ether 60-40 was used to defat both neem and tulsi leaves. 100 grammes of plant material were extracted for three hours with 500 ml of ethanol. A rotary evaporator was used to evaporate the extract, and the ethanol extracts that were produced were then conserved for future research in a dessicator. A poly herbal cream was created by mixing the extracts with other components and excipients. Numerous assessment criteria, such as pH, viscosity, spreadability, centrifugation test, spectrophotometric test, accelerated stability studies, and microbial stability, were used to assess the cream. In a stability chamber, the accelerated stability investigations were conducted for 20 days at both room temperature and an enhanced temperature.After centrifugation, stability testing, and no phase separation was observed, the cream was determined to be stable. E. coli and yeast growth were used to assess the microbiological stability. The outcomes showed that the cream's microbiological stability contained no microbial growth.

Keywords: Azadirachita indica, Ocimum sanctum, Evaluation, Poly herbal, Stability