A Review: Oral Antidiabetic Drugs

Abstract

Diabetes mellitus is a metabolic disorder caused due to insufficiency of insulin; type 2 (T2DM) is the most prevalent form of diabetes. The prevalence of diabetes is growing rapidly worldwide; India has the second highest number of people with diabetes in the world. The main goal in diabetes management is to improve patient’s quality of life, this can be achieved with better glycemic management and minimizing complications caused by hyperglycemia.

Metformin drug has been shown to prevent diabetes in people who are at high risk and decrease most of the diabetic complications. Recent report on metformin, not only indicate some implication such as renoprotective properties have been suggested for metformin, but some reports indicate its adverse effects as well that are negligible when its benefits are brought into account. The present review summarizes the various antidiabetic drugs for the treatment of diabetes mellitus.

Keywords: Diabetes mellitus, Antidiabetic drugs, Metformin, Blood glucose