Formulation and Evaluation of Mouth Dissolving Tablets of Montelukast Sodium

Abstract

Convenience of administration and increased patient compliance are critical factors in the design of oral drug delivery systems, which continue to be the dominant route of drug delivery despite several drawbacks. Mouth dissolving tablets (MDTs) have grown in popularity over the past decade, and the sector has developed into a fast-growing segment of the pharmaceutical business. Due to the formulation's popularity and use, various MDT technologies have been developed. These procedures enable to dissolve in the mouth in five seconds without the need for chewing or water, which is very beneficial for children, geriatrics, and people who have difficulty swallowing tablets and capsules. By addressing swallowing difficulties and limited patient compliance, the formulation of an appropriate dose form for administration results in the production of mouth dissolving tablets. There are various traditional ways of preparation of MDTs, however new technologies have been created for the manufacturing of mouth dissolving tablets.

Keywords: MDTs, Montelukast Sodium