A REVIEW ON CONTROLLED POROSITY OSMOTIC PUMP TABLETS AND ITS EVALUATION

Abstract

The objective of present review was to delivery of drugs in controlled pattern over a long period of time by the process of osmosis .Osmotic devices are the most promising strategy based systems for controlled drug delivery .They are the most reliable controlled drug delivery systems and could be utilized as oral drug delivery systems. The present review is concerned with the study of drug release systems which are tablets coated with walls of controlled porosity. When these systems are exposed to water, a low level of water soluble additive is leached from polymeric material. Semipermeable membrane and drug releases in a controlled manner over an extended period of time. Drug delivery from this system is not influenced by the different physiological factors within the gut lumen and the release characteristics can be predicted easily from the known properties of the drug and the dosage form. In this paper, the basic components of controlled porosity osmotic pump tablets have been discussed briefly.

Keywords: Osmotic pump, controlled-porosity osmotic pump tablet, semipermeable membrane, osmogent.