A NOVEL DRUG DELIVERY SYSTEM

Abstract

Microspheres are free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and they ideally have a particle size less than 200 µm. The magnetic targeted drug delivery system is one of the most attractive and promising strategy for delivering the drug to the specified site. Magnetic microsphere is a small particle, with diameter ranging between 1-1000 µm. Magnetic microsphere is occasionally referred to as microparticles. A magnetic Microsphere shows a great potential for future tests in the treatment. Magnetic microspheres as an alternative to traditional radiation methods which uses highly penetrating radiations that is absorbed throughout the body. Magnetic microspheres deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without unexpected effects. It has limited toxicity and side effects. Magnetic microspheres show two major problems 1.encountered in drug targeting 2.RES clearance. This paper gives an overview of the mechanism, benefits, drawbacks, preparations and applications of magnetic microspheres.