FORMULATION AND CHARACTERIZATION OF PHYTOSOMES OF SARACA ASOCA

Authors

  • Ayush Surana College of Pharmacy, Sri Satya Sai University of Technology and Medical Sciences, Sehore (M. P.)
  • Firoz Khan College of Pharmacy, Sri Satya Sai University of Technology and Medical Sciences, Sehore (M. P.)
  • Abdul Wajid Ali College of Pharmacy, Sri Satya Sai University of Technology and Medical Sciences, Sehore (M. P.)
  • C.K. Tyagi College of Pharmacy, Sri Satya Sai University of Technology and Medical Sciences, Sehore (M. P.)
  • Prabhakar Budholiya College of Pharmacy, Sri Satya Sai University of Technology and Medical Sciences, Sehore (M. P.)

Keywords:

Saraca Asoca, Phytosome complex, Drug content, Drug entrapment efficiency, Percentage yield, In-vitro drug release.

Abstract

The objective of the study was to develop a novel Phytosome formulation of Saraca Asoca by incorporation of phospholipids, for the improved permeability, solubility and better physical characteristics. The formations of phytosomes were analyzed for SEM, measurement of particle size, drug content, drug entrapment efficiency, Percentage yield, In-vitro drug release studies and also the release kinetics of Saraca Asoca phytosomes complex. The drug content, drug entrapment efficiency, SEM, measurement of particle size and other In-vitro drug release studies were resulted as anticipated. The Saraca Asoca phytosomes were found to show better solubility and compatibility with the excipients, it is concluded that Saraca Asoca phytosomes has better physical characteristics and improved permeability, solubility than that drug to overcome ability to cross lipid-rich biological membranes and which results in increase oral bioavailability.

Keywords: Saraca Asoca, Phytosome complex, Drug content, Drug entrapment efficiency, Percentage yield, In-vitro drug release.

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Published

2021-03-22

Issue

Vol. 9 No. 3 (2021)

Section

Articles