FORMULATION AND EVALUATION OF HERBAL EFFERVESCENT GRANULES INCORPORATED WITH MARTYNIA ANNUA EXTRACT

Abstract

The present research work is based on the formulation of herbal effervescent granules by incorporating the crude petroleum ether extract of martynia annua. The folklore of India widely uses this plant for treatment of various diseases and disorder. The dried leaves powder of the plant was extracted and subjected to preliminary chemical tests. Then it was formulated into efferevescent granules and then evaluated for various parameters like angle of repose, dissolution studies, and effervescent cessation time. The preliminary chemical studies show that the extract contains flavonoids, carbohydrate, alkaloids and glycoside. The formulated effervescent granules exhibited excellent flow properties which showed good angle of repose, carr’s index, Hausner’s ratio, bulk density and Tapped density.

KEY WORDS: Martynia Annua, Effervescent Granules, Carr’s Index, Hausner’s Ratio,