A Study on Bilayer Tablets for the Anti-Allergic Drug
Keywords:Tablets, bilayer tablet, physical mechanisms, drugs, Anti-Allergic, Allergic Rhinitis
The bilayer tablet formulations used for each individual layer should be compressible (i.e., the capacity of a material to undergo a reduction in volume as a result of an applied pressure) and compactable (i.e., the capacity of a powder to be transformed into tablets with strength during densification) on their own, i.e., they should show satisfactory reduction in volume and form mechanically sound and coherent solid bodies. A bigger contact area exists between the layers as a result of the increased surface roughness, which improves interlayer adhesion. Bilayer tablet characterisation in early formulation development has certain advantages, including Bilayer tablet interfacial strength should be quantified, unusual or extreme properties of compacted layers should be identified, lot-to-lot consistency of the produced tablets should be ensured, rational formulation development strategy followed, material failure mechanisms during tablet manufacturing should be explained, and tablet-specific factors' effects should be understood.